APA and MLA are two of the most commonly used citation styles. They are both used to cite sources in academic writing, but they have some key differences. APA is primarily used in the social sciences, while MLA is used in the humanities. APA emphasizes the date of a work, while MLA focuses on the author's name. APA also requires the use of a title page, while MLA does not. Finally, APA requires a reference list at the end of the document, while MLA requires a works cited page.